Wells in the Media

Skin nodule side effects after anti-aging procedure? Need to identify the cause and find appropriate countermeasures
2023.02.10
"<p>[mdtoday=Reporter Ko Dong-hyeon] It is frequently observed that anti-aging procedures performed to improve fine wrinkles, enhance skin elasticity, and restore volume end up causing side effects that become a source of stress. To what extent can the various side effects arising from procedures undergone in hopes of returning to a naturally youthful appearance be prevented and treated?</p>
<p>Dermatological procedures are generally less burdensome in many respects than plastic surgery, which involves incisions and requires a lengthy recovery process involving bleeding, severe swelling, and bruising. For this reason, more people tend to try them with relative ease. Sculptra, one of the currently popular anti-aging procedures, has far fewer side effects compared to surgery or other procedures such as fillers, though skin nodules can rarely occur.</p>
<p>Sculptra is a procedure in which powdered PLLA is mixed with saline solution and injected beneath the skin. The PLLA induces collagen production, restoring skin elasticity and replenishing volume to deliver an anti-aging effect. It offers the advantage of enabling natural volume restoration with minimal pain, and the volume improvement effect—particularly in areas such as the cheeks and temples—is noted to be quite dramatic.</p>
<p>Compared to filler procedures, which involve injecting a gel-like substance that can potentially block blood vessels, Sculptra—which involves injecting a solution—is considered an extremely safe procedure with no risk of side effects such as blindness or necrosis. The only known side effect, skin nodules, consists of firm, palpable lumps approximately the size of a bean, formed when self-generated collagen clusters together.</p>
<p> <img src="https://cdn.mdtoday.co.kr/news/photo/202208/441795_1_2342.jpg" alt="" style="max-width:100%"> </p>
<p>In the cheek and nasolabial fold areas, which are among the most commonly treated sites, skin nodule symptoms—even when they do occur—are generally not visible on the surface and are only felt upon deep palpation, so they rarely pose a cosmetic concern. Furthermore, when nodules are addressed appropriately in the early stages of onset, they can typically be resolved without significant issue, making it debatable whether they should even be classified as a side effect.</p>
<p>Nevertheless, there are clear reasons why the number of people experiencing stress due to Sculptra-related skin nodules continues to increase.</p>"
"<p>The reasons for this include procedures carried out indiscriminately by non-specialists, insufficient skill in properly analyzing each individual's skin characteristics and features, inaccurate dosage amounts, and the use of substandard Sculptra.</p>
<p>For Sculptra treatments, it is important to reflect each individual's skin characteristics and anatomical features through 3D analysis and to predict customized dosage amounts. In addition, one must not be negligent in the process of verifying whether a clinic uses genuine Sculptra and guarantees accurate concentration levels, pre-mixes an adequate ratio of normal saline solution thoroughly, uses area-specific customized cannulas, and strictly adheres to safety protocols.</p>
<p>Dr. Ryu Hyo-seop, director of Well Dermatology Clinic Apgujeong Main Branch, explained, "Skin nodules, known as a side effect of Sculptra, have an extremely low probability of occurring if the appropriate amount is accurately predicted before the procedure and a customized dosage is precisely injected into the necessary areas. However, even if nodules do develop due to treatment by a non-specialist or other reasons, there is no need for great concern."</p>
<p>He added, "This is because the nodules are composed of collagen produced by the body itself, not a foreign substance, so improvement is possible by consulting a dermatology specialist to thoroughly identify the cause and receiving consistent treatment through customized procedures."</p><p>Medical Today Reporter Ko Dong-hyun (august@mdtoday.co.kr)</p>
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